腺病毒疫苗和灭活疫苗的优缺点一览(腺病毒疫苗)
腺病毒疫苗和灭活疫苗的优缺点一览(腺病毒疫苗)，
关于新冠疫苗大家有很多想要了解的，国内新冠疫苗就三种，分别是腺病毒疫苗、灭活疫苗、重组蛋白疫苗。这三种疫苗如何选择大家也比较关注，腺病毒疫苗和灭活疫苗的优缺点是什么呢？之间的区别有哪些？本专题将针对腺病毒疫苗和灭活疫苗给大家详细介绍下。
接种腺病毒载体疫苗的好处：
对于有临时或紧急任务需要前往疫区、却没有足够时间等待的人群，更适合注射单针腺病毒载体疫苗。
1、单针接种即完成了全程免疫，避免了因路途遥远、工作繁忙或疫苗匮乏打不上第二针造成的免疫脱落，保障了高疫苗接种率;
2、单针注射总体成本较低，成本效益比更高。
3、在当前全球疫苗产能不足的情况下，单针疫苗可接种双倍人群，提高了疫苗的可及性。
缺点
单针腺病毒载体疫苗诱导的免疫反应强度一般弱于两针疫苗。因为这类疫苗再次接种时，人体主要产生针对“汽车”——腺病毒载体，而不是“货物”——“新冠病毒抗原基因”的记忆反应。这类单针疫苗在预防早期的流行病毒时没问题，换成后期突变病毒时，保护效率大多会下降。
灭活疫苗的优缺点：
将病原微生物（包括细菌、病毒和立克次体等）及其代谢产物用物理或化学的方法使其灭活，丧失毒力，但仍保留其免疫原性而制成的疫苗，如百日咳疫苗、流脑疫苗等。这种疫苗由于病原微生物已被杀，进入人体后不能生长繁殖，因此需要注射剂量大，注射次数多。一般注射一针后产生免疫力不高，需要注射2～3次或加强注射，才能产生较为满意的免疫力。但是，灭活疫苗的稳定性好，容易保存。
更多的疫苗信息关注下面：
其他拓展知识
*:研究人员给志愿者接种两针灭活疫苗后,再接种一针腺病毒载体新冠疫苗作为加强,14天后中和抗体GMTs为197.4 (167.7, 232.4),抗体水平升高约78倍;若第三针用灭活...
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